WebDec 1, 1996 · Watanabe KH, Bois FY, Daisey JM, Auslander DM, Spear RC. Benzene toxicokinetics in humans: exposure of bone marrow to metabolites. Occup Environ Med. 1994 Jun; 51 (6):414–420. [Europe PMC free article] [Google Scholar] Docter HJ, Zielhuis RL. Phenol excretion as a measure of benzene exposure. Ann Occup Hyg. 1967 Oct; 10 … Webbenzene and how this information does or does not provide insights as to the mode of action of benzene or if there is a consensus as to the metabolites of benzene responsible for toxicity. RESPONSE: The agency agrees with the peer panel and has expanded discussion of section 3.3 to facilitate a better understanding of these concepts. 12.
ATSDR Benzene ToxGuide - Agency for Toxic Substances and Disease Registry
WebToxicokinetics. Toxicokinetics is defined in ICH Guideline S3A as ‘the generation of … WebCHAPTER 3. TOXICOKINETICS, SUSCEPTIBLE POPULATIONS, BIOMARKERS, CHEMICAL INTERACTIONS . 3.1 TOXICOKINETICS Toxicokinetic data for DDT, DDE, and DDD are summarized below. • DDT, DDD, and DDE are absorbed following inhalation, oral, or dermal exposure, but humans are predominately exposed via the oral route. cytology actinomyces
Toxicokinetics of benzene, toluene and xylenes - PubMed
WebToxicokinetics of benzene, toluene and xylenes . Author A Sato 1 Affiliation 1 Department … Webbenzene and 44 age- and gender-matched unexposed controls. Of the 44 subjects in the … WebChapter 5.2 Benzene Air Quality Guidelines - Second Edition WHO Regional Office for Europe, Copenhagen, Denmark, 2000 3 In a study carried out in Germany in 1990–1991 (12) with 113 persons selected at random over the country, the geometric mean of personal exposure to benzene was found to be 11 µg/m3 ; the 95- percentile was 32 µg/m3.Some … cytology advantages and disadvantages