2024 Phf14

Phf14

Author: lupp

August undefined, 2024

Web7. okt 2024 · 7D86, 7D87, 7D8A. PubMed Abstract: Histone recognition constitutes a key epigenetic mechanism in gene regulation and cell fate decision. PHF14 is a conserved multi-PHD finger protein that has been implicated in organ development, tissue homeostasis, and tumorigenesis. Here we show that PHF14 reads unmodified histone H3 (1-34) through an ... Web23. jún 2012 · Phf14 / MEF showed higher levels of p38 and ERK phosphorylation than Phf14 / MEF. *, p 0.05 versus Phf14 / (n 3). B, inhibition of ERK activity, but not p38 activity, can suppress the growth of ...

Silencing expression of PHF14 in glioblastoma promotes …

Web7. okt 2024 · PHF14 is a conserved multi-PHD finger protein that has been implicated in organ development, tissue homeostasis, and tumorigenesis. Here we show that PHF14 reads unmodified histone H3(1-34) through an integrated PHD1-ZnK-PHD2 cassette (PHF14PZP). Our binding, structural and HDX-MS analyses revealed a feature of bipartite … albemarle center console for sale

UniProt

Web3. jan 2024 · Abstract. PHF14 is a newly identified regulator of mesenchyme growth in embryonic tissues. Previous studies have shown that phf14-null mutants die just after … WebPHF14. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. WebPHF14 Promotes Cell Proliferation and Migration through the AKT and ERK1/2 Pathways in Gastric Cancer Cells. Study revealed that miR-590 was shown to directly target PHF14 … albemarle chemical

DAXX - PHF14 Interaction Summary BioGRID

WebA Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances. The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. Web1. dec 2024 · 3.2. PHF14 is needed for the proliferation of GC B cells. In the further analysis, we explored the reason for decreased GC formation and revealed a skew in dark zone and … albemarle cio ravi waranWebIn addition, PHF14 suppressed the expression of Cdkn1a (p21) though regulating the level of H3K4me3 to control the proliferation of GC B cells. Collectively, our data suggest that … albemarle charlottesville spca

"Web27. nov 2024 · PHF14, a member of the PHD finger protein family, is coded by a highly conserved gene found in the 19p13.2 chromosomal region . PHF14 has been described as a modulator for mesenchymal cells proliferation in alveolar tissues [20, 21], as well as a novel hypoxia-sensitive epigenetic regulator in cell proliferation . However, the biological ... " - Phf14

Phf14

WebPrestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution. Synonym (s): Anti-PHD finger protein 14 antibody produced in rabbit. Human Protein Atlas Number: HPA000538. Pricing and … Web1. aug 2013 · Three transcripts of PHF14 in human cell lines were identified by reverse transcriptase polymerase chain reaction. Two isoforms of PHF14 (PHF14α and PHF14β) …

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Webphf14全长含有3-4个phd锌指结构域。作为一类表观调控因子，phf14在胚胎发育，癌症发生和组织稳态维持等过程中均发挥着重要作用。例如，纯合敲除phf14的小鼠在出生几个小 … WebPrestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution. Synonym (s): Anti-PHD finger protein 14 antibody produced in …

WebPHF14 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, PHF14 Genome Browser, PHF14 References PHF14 - Explore an overview of PHF14, with a … WebAntibodies that detect PHF14 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and …

Web1. dec 2024 · PHF14 regulates the proliferation of GC B cells by p21. The GC B cells from the spleen of PHF14 GCB KO and PHF14 GCB KO mice 7 d after SRBC immunization were sorted and analyzed by RNA-seq. We found increased mRNA of Cdkn1a (p21) in the GC B cells from PHF14 GCB KO mice than the PHF14 GCB WT mice ( Fig. 4 A). WebDownload scientific diagram Upregulation of PHF14 in lung cancer is significantly associated with poor prognosis. A. PHF14 expression in paired NSCLC samples (n=44). Left panel: representative ...

WebPHF14 is a member of the PHD finger protein family that serves as a chromatin-binding protein. It contains four putative PHD fingers, two coiled-coil regions, and four zinc fingers. PHF14 is highly conserved from C. elegans to humans and is considered as a transcriptional regulator of target gene expression.

WebUsing a knockdown screen, Kitagawa et al. (2012) identified Phf14 as a regulator of proliferation in MEFs. Using a proteomic approach with coimmunoprecipitation, Huang et … albemarle clinicPHF14 (PHD Finger Protein 14) is a Protein Coding gene. Diseases associated with PHF14 include Ceroid Lipofuscinosis, Neuronal, 9 and Dandy-Walker Syndrome . An important paralog of this gene is BRD1 . albemarle chinaWeb21. jan 2024 · Knockdown of PHF14 mediated severe DNA damage and activation of the ATR-CHK1-H2A.X pathway, leading to apoptosis. Strikingly, PHF14 interacted with KIF4A and contributes to the formation of BRCA2/Rad51 foci, indicating that PHF14 is a newly discovered factor that may participate in the formation and recruitment of DNA damage … albemarle charlotte ncWeb27. nov 2024 · PHF14 has been described as a modulator for mesenchymal cells proliferation in alveolar tissues [ 20, 21 ], as well as a novel hypoxia-sensitive epigenetic … albemarle ci ncWeb10. apr 2024 · PHF14 plays an oncogenic role in CRC, and the mutation rate of PHF14 in CRC patients was as high as 18%. • PHF14 interacts with KIF4A contributes to the formation … albemarle co gisWeb10. jún 2024 · PHF14 is involved in multiple biologic processes including Dandy-Walker syndrome, mesenchyme growth, lung fibrosis, renal fibrosis, persistent pulmonary … albemarle co school calendarWeb28. feb 2024 · Given that SIRT1 is a protein deacetylase, we tested whether PHF14 could favour protein acetylation. Indeed, PHF14 and associated proteins were already proposed to function by counteracting the function of the repressive LSD1-CoREST complex, which contains histone deacetylases along the H3K4 demethylase (Garay et al., 2016; Wynder et … albemarle competitors